Introduction:
Puerto Rico (PR) is a unincorporated territory of the United States, located in the Caribbean. It is estimated that more than 3.2 million people live in the archipielago.1 Nearly 51,610 people have been diagnosed with HIV/AIDS in PR since the beginning of the epidemic.2 San Juan, Puerto Rico is one of the 48 jurisdictions (+Washington, DC) accounting for more than 50% of all new HIV diagnoses in the U.S. Puerto Rico has one of the highest HIV rates, with a prevalence of 564.1 x 100,000 diagnosis rate (for 2020). By February 2023, 51,463 persons had been diagnosed with HIV and AIDS in PR. In PR, 79.1% of HIV/AIDS cases are among men, of which 71% are sexual minority men (SMM)3.

Pre-Exposure Prophylaxis (PrEP) is a highly effective medication to reduce the risks for HIV infection. PrEP uptake among Latinxs in Puerto Rico is the lowest in the United States (U.S.). 4 Yet, this population continues to be highly impacted by the HIV epidemic. Despite the promising opportunity to reduce the number of new HIV infections, as of 2021, only 343 individuals were using PrEP in Puerto Rico.5 The PrEP care continuum illustrates a sequence of steps, including main benchmarks: Awareness, Uptake, and Adherence and Retention. The continuum is a reference for developing effective interventions and measuring public health progress in PrEP program implementation.